InterMed Discovery

Tuesday, September 07, 2010

Dr. Joachim Hans

Director Flavour Ingredients,
Plant Sourcing Manager

Dr. Joachim Hans studied biology at the University of Tübingen and moved on to the Leibniz-Institute of Plant Biochemistry in Halle (Saale) for his PhD, focusing on plant natural products accumulating in symbiotic plant-fungus interactions. After a short stay as a PostDoc at the Scottish Crop Research Institute (SCRI, Dundee, UK) he took on a position as Scientific Employee / Head of Laboratory at the Department of Pharmaceutical Biology, University of Marburg, investigating biosynthetic pathways for natural products in medicinal plants. Dr. Hans has 7 years of experience in plant natural product research with a strong background in plant protein biochemistry and molecular biology. He joined InterMed Discovery in April 2008 as Research Scientist and Plant Sourcing Manager.

Education and Professional Career
Since 04/2008 Director Flavour Ingredients and Plant Sourcing Manager at InterMed Discovery GmbH
2006–2008 Scientific Employee and Head of Laboratory at the Dept. of Pharmaceutical Biology, University of Marburg
2004–2005 PostDoc at Scottish Crop Research Institute in Dundee, UK
2004 PostDoc at Leibniz-Institute of Plant Biochemistry in Halle (Saale), Dept. Secondary Metabolism
1999–2004 PhD thesis at Leibniz-Institute of Plant Biochemistry in Halle (Saale), Dept. Secondary Metabolism
1998–1999 Diploma thesis at University of Tübingen, Dept. Ecological Plant Physiology
1992–1998 Biology studies at University of Tübingen

 

Publications

Bengough AG, Hans J, Bransby MF, Valentine TA (2009) PIV as a method for quantifying vell growth and particle displacement in confocal images. Microscopy Research Technique, published online 17 Jun 2009

Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (2009) Isolation and fucntional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis. Journal of Biological Chemistry 284, 4776-4785

Rohde B, Hans J, Martens S, Baumert A, Hunziker P, Matern U (2008) Anthranilate N-methyltransferase, a branch point enzyme of acridone biosynthesis, Plant Journal 53, 541-553.

Larbat R, Kellner S, Specker S, Hehn A, Gontier E, Hans J, Bourgaud F, Matern U (2007) Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis Journal of Biological Chemistry 282, 542-554.

Walter MH, Floß DS, Hans J, Fester T, Strack D (2007) Apocarotenoid biosynthesis in arbuscular mycorrhizal roots: Contributions from methylerythritol phosphate pathway isogenes and tools for its manipulation Phytochemistry 68, 130-138.

Bengough AG, Bransby MF, Hans J, McKenna SJ, Roberts TJ, Valentine T (2006) Root responses to soil physical conditions; growth dynamics from field to cell Journal of Experimental Botany 57, 437-447.

Hans J (2004) Isoprenoidbiosynthese in mykorrhizierten Maiswurzeln: Klonierung, Charakterisierung und Lokalisierung einer 1-Desoxy-D-xylulose-5-phosphat-Reduktoisomerase (DXR), PhD Thesis University of Halle.

Hans J, Hause B, Strack D, Walter MH (2004) Cloning, characterization and immunolocalization of a mycorrhiza-inducible 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) in arbuscule-containing cells of Zea mays Plant Physiology 134, 614-624.

Walter MH, Hans J, Strack D (2002) Two distantly related genes encoding 1-deoxy-D-xylulose 5-phosphate synthases: differential regulation in shoots and apocarotenoid-accumulating mycorrhizal roots Plant Journal 31, 243-54.

Posters

Kellner S, Specker S, Hans J, Matern U “Elicitor-induction, molecular cloning and characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis in Ammi majus L.” 8th International Symposium on Cytochrome P450 Biodiversity and Biotechnology, 23.-27. July 2006, Swansea, Wales, UK.

Hans J, Strack D, Walter MH “Characterization and localization of a maize 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) induced during apocarotenoid biosynthesis in mycorrhizal roots”; 6. Terpnet Meeting, 14.-17. May 2003, Lexington KY, USA.

Hans J, Strack D, Walter MH “Isoprenoid biosynthesis in mycorrhizal maize roots: transcript and protein accumulation of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR)”; 19th Annual Meeting of the International Society of Chemical Ecology (ISCE), 3.-7. August 2002, Hamburg, Germany.

Oral presentations

Hans J, Kellner S, Matern U “Furanocoumarin biosynthesis in Ammi majus: Cloning and characterization of psoralen synthase, the first pathway-specific cytochrome P450”; Botanikertagung, 03.-07. September 2007, Hamburg, Germany.

Hans J “Computer visualisation of root morphogenesis – Optical flow analysis of time-lapse confocal microscopy images”; Scottish Root Group Meeting, 17. November 2005, Dundee, United Kingdom.

Hans J “Isoprenoid biosynthesis in mycorrhizal maize roots – Characterization and localization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR)“; Institut de Biologie Moléculaire des Plantes CNRS, 19. August 2005, Strasbourg, France.

Hans J “Isoprenoid biosynthesis in mycorrhizal maize roots: cloning, characterization and immunolocalization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase”; Plant Biochemistry Seminar Series, Institute of Biological Chemistry, Washington State University, 16. September 2003, Pullman WA, USA.

Hans J, Strack D, Walter MH “Isoprenoid biosynthesis in mycorrhizal maize roots: Immunolocalization of a mycorrhiza-inducible 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR)“; 4. Colloquium of DFG Focus Program “Molecular Basics of Mycorrhizal- Symbioses“, 12.-14. December 2002, Wittenberg, Germany.

Hans J “Transcript and protein accumulation of a 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) in mycorrhizal maize roots“; 4th Kurt-Mothes Workshop; 3.-5. October 2002, Jena, Germany.