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- Dr. Ernst Roemer
Dr. Ernst Roemer
Intellectual Property Manager
Dr. Ernst Roemer studied chemistry in Braunschweig and obtained his PhD in 1992. Prior to InterMed Discovery he joined the Hans-Knöll-Institute (Jena) and the Institute of Plant Biochemistry (Halle). He is an expert in Natural Products research with more than 15 years experience. He joint InterMed Discovery in 2006 as Intellectual Property Manager being responsible for all IP related activities.
His responsibilities include all processes in order to protect the intellectual property at IMD. Amongst others this comprises the literature research to secure freedom to operate in all interesting application fields, the identification of the chemical matter to get a broad protection and monitoring of the competitor situation and possible infringements. Together with our external patent attorneys he develops the patent strategy for the entire life cycle.
| Professional Career | |
|---|---|
| since 10/2006 | InterMed Discovery GmbH |
| 2006–2007 | Database Manager at the Leibniz-Institute for Plant Biochemistry, Halle |
| 2000–2006 | Project leader at the Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena |
| 1995–2000 | Scientific employee at the HKI, Jena |
| 1993–1995 | Postdoctoral research fellow at Prof. Dr. U. Gräfe, HKI, Jena |
| 1992–1993 | Postdoctoral research fellow at Prof. Dr. K. Krohn, University of Braunschweig |
| 1989–1992 | Ph.D. studies, University of Braunschweig |
Publications
Papers
"Biologically active metabolites from fungi. Phomosines A-C, 3 new biaryl ethers from phomopsis sp.", K. Krohn, A. Michel, E. Roemer, U. Flörke, H.-J. Aust, S. Draeger, B. Schulz, V. Wray; Nat. Prod. Lett. 9, 1995, 309–314.
"Synthesis of 4-Deoxyaklanonic acid and Its Microbial Conversion into Anthracyclinones", K. Krohn, E. Roemer, M. Top, C. Wagner; Angew. Chem. 105, 1993, 1220-1221, Angew. Chem. Int. Ed. Engl. 32, 1993, 1151 – 1152.
"Total Synthesis of Aklanonic Acid and Derivatives by Baker-Venkataraman Rearrangement", K. Krohn, E. Roemer, M. Top; Liebigs Ann. Chem. 1996, pp. 271-277.
"Neue polycyclische Phthalazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung", L. Heinisch, U. Gräfe, E. Roemer, W. Werner, U. Möllmann; AZ 19633221.4, 17.8.1996.
"Semisynthetic Derivatives of Madurahydroxylactone and Their Antibacterial Activities", L. Heinisch, E. Roemer, P. Jütten, W. Haas, W. Werner, U. Möllmann; J. Antibiotics 52, 1999, 1029 - 1041.
"A multicopper oxidase gene from Candida albicans: cloning, characterization and disruption", R. Eck, S. Hundt, A. Härtl, E. Roemer, W. Künkel; Microbiology 145, 1999, 2415 - 2422.
"Regioselective Synthesis of Benzo[g]isoquinoline-5,10-dione Derivatives as DNA Intercalators", A. Opitz, E. Roemer, W. Haas, H. Görls, W. Werner, U. Gräfe; Tetrahedron 56, 2000, 5147 - 5155.
"Lydiamycins A-D: a New Class of Small Cyclodepsipetides with Anti-Mykobacterial Properties", X. Huang, E. Roemer, I. Sattler, U. Moellmann, A. Christner, S. Grabley; Angew. Chemie Int. Ed. Eng. 2006.
"Identification of a specific inhibitor of the histone methyltransfease SU(VAR)3-9", D. Greiner, T. Bonaldi, R. Eskeland, E. Roemer, A. Imhof; Nature Chem. Biol. 2005.
Patent applications
"New polycyclic phthalazin derivatives and their use", L. Heinisch, U. Möllmann, W. Witte, C. Cuny, E. Roemer, W. Werner, W. Gräfe; WO9807706.
"Preparation of madura hydroxylactone comprises cultivating Nonomuria rubra or derivatives and isolating product", M. Roth, K. Perlet, E. Roemer, M. Hilliger, L. Heinisch, K.-D. Menzel; DE19845580.
"Preparation of madura hydroxylactone comprises cultivating Nonomuria rubra or derivatives and isolating products", M. Roth, K. Perlet, E. Roemer, M. Hilliger, L. Heinisch, K.-D. Menzel; DE19845580.
"Treating cytokine-mediated diseases, e.g. asthma, allergy, eczema, rheumatoid arthritis or transplant rejection, using new or known maduraphthalazine derivatives", R. Draheim, T. Kronbach, L. Heinisch, E. Roemer, N. Höfgen, H. Poppe, P. Jütten, W. Haas, W. Werner, U. Gräfe; WO0063181.
"Griseusin derivatives and their use as antitumor agents", S. Grabley, I. Sattler, E. Roemer, X. Huang, J. He, H. H. Fiebig, A. Maier, G. Kelter; EP1650209.
"New lydiamycin cyclodepsipeptides useful for controlling diseases cause by mycobacteria, e.g. tuberculosis and leprosy", X. Huang, E. Roemer, I. Sattler, U. Möllmann; DE102004046142.
"Plants extracts for use in brain modulation", T. Grothe, E. Roemer; EP 06026244.
Posters
"Madurahydroxylactone: Derivating and Activities", E. Roemer, L. Heinisch. U. Möllmann, W. Haas, P. Jütten, W. Werner; Nashville, 1994, 4th Int. Conf. on Chemical Syntheses of Antibiotics and Related Microbial Products.
"Instrumentalanalytische Hochleistungsmethoden zur Detektion und Strukturaufklärung von Naturstoffen und chemischen Substanzen", U. Gräfe, E. Roemer, A. Berg, W. Werner; Leipzig, 17. - 20. September 1997, Innovationsmesse.
"Combinatorial Solid-Phase Synthesis with Natural Products: New Antihypertensive Ergolin Analogs", E. Roemer, Y.-Q. Tang, R. Wyrwa, A. Härtl, E. Glusa, S. Grabley, R. Thiericke; Tübingen, August 1999.
"AWD 72-011, A novel selective Inhibitor of the Biosynthesis of Interleukin-5", R. Draheim, E. Roemer, H. Poppe, L. Heinisch, T. Kronbach, N. Höfgen; Edinburgh May 2001.
"Piperazinsäure-haltige Antibiotika aus Actinomyceten. I. Aurantimycin und Verucopeptin. II. Ein neues antimikrobielles Cyclopeptid aus Streptomyces lydiacus", X. Huang, E. Roemer, Isabel Sattler; 25. Tübinger–Göttinger Gespräche zur Chemie von Mikroorganismen.
Oral presentations
"Biomimetische Totalsynthese von Aklanonsäure", E. Roemer; Jena, 27.4.1993.
"Kombinatorisch-diversifizierende Synthese lipophiler Liganden für dreiwertiges Eisen nach dem Vorbild der Natur", U. Gräfe, E. Roemer; SFB 1486, 8. Januar 1997.
"The Virtual Natural Products Pool", E. Roemer; Freiburg, 2004.